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Metformin: An old but still the best treatment for type 2 diabetes
Metformin is the basic medicine prescribed to type 2 diabetes patients who are overweight. It is one of the oral forms of medicines that improve the overall level of blood sugar. In addition to the use of Metformin for diabetes, it is also used for the polycystic ovarian syndrome (PCOS) in women. The first line oral agent is one of the oldest but the best suited for its antihyperglycemic properties.
The purchase metformin without prescription makes it one that offers quicker and easier access. In addition to the glycemic control, Metformin improves endothelial dysfunction, hemostasis and oxidative stress, insulin resistance, lipid profiles, and fat redistribution. The drug belongs to the family known as biguanides, which work by reducing glucose during digestion.
Metformin Uses And Working
One can order metformin cash on delivery from the nearest pharmacy store or an online drug store. Basically used to treat the high blood sugar levels of the type 2 diabetes patients, this is an oral medication commonly taken in combination with diet and exercise. Sometimes, the patient might be involved in the uses of Metformin as part of the therapy and can involve a high intake of the drug but under the supervised and prescribed conditions.
Metformin is only biguanides that are available in most of the countries. While you plan to buy metformin online, it is equally important to know the drug's basic working. It works by:
- Reducing glucose secretion by the liver during the digestion process
- Reducing the amount of glucose that can be absorbed by the body
- Increasing the level of natural insulin in the body
Metformin Administration and Dosage
The first advice is to take the Metformin in the same manner as prescribed by the physician. It will assure that no Metformin overdose can have adverse effects on health and overall well-being.The dosage of the Metformin is largely dependent on various factors like:
- Age of the patient
- Type and severity of the condition
- Form of Metformin
- Any other medical condition
The typical dose of Metformin differs for people of different age groups.
- For an adult between ages 18-79, the typical dose of the immediate-release tablets would be 500mg twice a day or 850mg once per day at the start and might increase with time under the physician's guidance. Additionally, if the tablets are Extended-release tablets, it would be 500mg once per day, usually during evening meals.
- For an adolescent of age 10-17 years, the immediate release tablets are only prescribed, and the dosage would be typically 500mg twice per day.
- Seniors above the age of 80 and children below the age of 10 are normally not suggested metformin. If a senior is prescribed one, it would be under extreme supervision.
While on medication, ensure to check the sugar levels. If it goes below the required levels causing dizziness, confusion, anxiety, shaky, or any other such symptom, then consult the physician immediately.
The overdose can cause various conditions like severe nausea, vomiting, diarrhoea, epigastric pain, thirstiness, lost appetite, lethargy and hyperpnoea. While the other prominent clinical symptoms of overdose that one can face include Hypotension, hypothermia, acute renal failure, coma and cardiac arrest. So, while you plan to Metformin 1000 mg cod online, check the requirement as per your age and condition to avoid any adverse effect.
Metformin Forms and Strengths
Metformin is the generic drug which comes in two forms. The immediate-release oral tablet is offered in three strengths, 500 mg, 850 mg, and 1,000 mg. The other form is the extended-release oral tablet with the strengths of 500 mg, 750 mg, and 1,000 mg. Apart from that, there are brand drugs that use the same salt. Some of the prominent ones are Glucophage, Glucophage XR, Fortamet, Glumetza, and Carbophage XR. You can buy Carbophage XR 500 mg pills online from different medical stores.
Before you start taking Metformin for diabetes, there are a few precautions to be taken, which are:
- Inform your physician about any allergy that you might have to Metformin.
- Let the physician know about medical history, especially related to severe breathing problems, blood problems, kidney disease, or liver disease.
- Excessive Metformin can cause blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar.
- While on Metformin, alcohol consumption needs to be limited as it can cause the risk of lactic acidosis.
- Metformin can increase the chances of being pregnant by changing the menstrual cycle.
- If prescribed to a pregnant woman, then make sure that sugar levels are maintained.
- The medicine is not advisable to be consumed while breastfeeding.
Drug interactions change the way a medicine works on its own. While you order metformin 500 mg online, make sure of the possible interactions with the other medicines you might be taking.One can surely contact the physician to know about the possible effects of the drug interactions before he plans to buy Carbophage XR Online. Still, some of the most common interactions are:
- Diabetes drugs: Using insulin or medication that releases insulin with Metformin can cause lower blood sugar levels.
- Blood pressure drugs: Diuretics drugs like furosemide and hydrochlorothiazide are used to lower blood pressure. It can increase the blood sugar level interfering with the effectiveness of Metformin.
- Cholesterol drug: Intake of the nicotinic acid with Metformin can adversely affect medicine's performance in reducing the sugar level.
- Glaucoma drugs: Drugs like acetazolamide, brinzolamide, dorzolamide, and methazolamide when used combined with the Metformin can increase the risk of lactic acidosis.
- Topiramate: It is used to treat nerve pains or seizures. But when used in combination with the Metformin can highly increase the risk of lactic acidosis.
- Phenytoin: Another medicine that is purely used to treat the seizures. The combination of metformin with phenytoin hinders the effectiveness of the metformin in reducing the blood sugar level.
- Stomach problem drugs: Drugs like cimetidine are used to serve the heartburn and stomach pains. When consumed with Metformin can cause the risk of lactic acidosis.
- Phenothiazines: The antipsychotic medications like chlorpromazine, fluphenazine, and prochlorperazine can hamper the effectiveness of Metformin.
- Hormone drugs: Basic hormone drugs, corticosteroids and estrogens, negatively affect the performance of the Metformin.
- Tuberculosis drug: Intake of isoniazid drug with Metformin reduces drug capacity g to lower the blood sugar level.
- Thyroid drugs: Drugs like desiccated thyroid, levothyroxine, liothyronine, and liotrix, are not supportive of Metformin.
The side effects of Metformin range from mild to severe ones. The most common forms of side effects that one can see when on Metformin are:
- Stomach Problems like diarrhoea, decreased appetite, heartburn, gas.
- Cough, fever or chills
- Breathing issues like paced breathing
- A general feeling of discomfort
- Body ache, back pain, muscle pain or cramping
- Sleepiness, unusual tiredness, and dizziness
- Anxiety, confusion, blurred vision, depression, and headache
- Nervousness, shakiness, slurred speech, or nightmares
- Rash, swollen joints, or discolouration of nails
- indigestion, vomiting, or abnormal weight loss
- Nausea or seizures
- Nightmares & restless sleep
Severe Metformin toxicity can cause serious side effects that might call for immediate medical attention. There are basically two conditions that the patient will need to look in:
- Lactic acidosis: The problem is one of the most serious and uncommon ones. It occurs due to the buildup of the metformin in the body and can cause trouble breathing. Some of the common symptoms are extreme tiredness, weakness, decreased appetite, nausea, vomiting, dizziness, and differentiated heart rate.
- Hypoglycemia: This is one of the conditions that are not likely to happen as it is linked to low blood sugar level, but it can happen if the intake of metformin is combined with a poor diet, strenuous exercise, excessive alcohol intake, or other diabetes medications
- Anaemia: Metformin is proven to decrease the level of vitamin B-12. This causes a reduction in the number of red blood cells. The most common symptoms are tiredness, dizziness, and lightheadedness.
If you face any of these symptoms or side effects, then contact your physician at the earliest. While you can buy metformin USA to USA, it is advisable to consult the physician before getting one.
This is one of the few drugs that come with the black box warning. If means when you plan to use Metformin for diabetes, then there is a warning alert associated with it that suggests the drug is dangerous for the patient, Apart, some other warnings that are associated with the uses of Metformin are:
- Alcohol use warning
- Kidney problems warning
- Liver problems warning
- Allergy warning
- Diabetic ketoacidosis warning
- Heart Problem warning
- Pregnancy warning
Take the metformin in the manner it is prescribed to you. Make sure to keep a check of the sugar levels. Even when you see improvements, do not change the dose or strength without being consulted with the physician. Ensure to take medicine with a proper diet. Keep the drug away from light and high temperature. A healthy lifestyle with proper intake of drugs can ensure better management of diabetic conditions.
Where to buy Metformin online
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